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June 11, 2013

PLANDAI’S PRODUCTS MAY INHIBIT PROSTATE CANCER GROWTH

Recent prostate cancer studies involving the use of green tea as a method of inhibiting prostate cancer growth demonstrate yet another major clinical market opportunity for Plandaí Biotechnology Inc. (OTCQB – PLPL - $0.54 – Spec Buy).  Plandaí develops highly bioavailable, phytonutrient extracts rich in anti-oxidant catechins (like EGCG) which it intends to utilize to deliver a new family of drugs to safely and affordably treat a multitude of diseases and conditions. 

Last week at the annual ASCO (Association of Clinical Oncology) conference, a group of doctors who conducted a study of 203 men diagnosed with prostate cancer at hospitals in Europe demonstrated that polyphenol-rich foods such as green tea demonstrated multiple anti-cancer effects. In fact, this is the first time that they have firmly established an influence on prostate-specific antigen (PSA) markers of cancer progression within a scientifically robust evaluation.

Prostate cancer is the second leading cause of cancer death among men in the U.S. and the sixth leading cause of cancer death among men worldwide.

It should be noted that the aforementioned six-month trial is not the first to study the effect of green tea on prostate cancer.  A recent two-month study at the University of California, Los Angeles (UCLA) demonstrated that the consumption of 6 cups of green tea daily might inhibit the growth of prostate cancer tumors by decreasing inflammation and stimulating cell death. The Phase 2 trial was randomized and included 67 subjects.  Once again, results showed that the polyphenols routinely reached the prostate. 

The key takeaway from both of these studies is that it is likely that increased bioavailability in the consumed product may result in increased efficacy. For example, instead of having trial subjects consume 6 cups of green tea daily, as was the case in the UCLA trial, it makes more sense to utilize a form of Plandaí's Phytofare™ Catechin Complex, which is processed to deliver a highly bioavailable, antioxidant- rich botanical green tea-derived extract at a level many times that of other products available on the market.  Therefore, not only would the subject reduce consumption, but the higher bioavailability could lead to greater efficacy as well.

Since a number of extended and new studies on the effect of green tea and prostate cancer are in the offing, we believe that Plandaí will benefit as a likely primary source of product for the trials and these moves potentially could result in a commercially available Plandaí-product used by consumers to prevent or treat prostate cancer.

For more information, refer to our previous PLPL Reports, Updates and Hot Topics by visiting www.GoldmanResearch.com

Senior Analyst: Robert Goldman
Rob Goldman has over 20 years of investment and company research experience as a senior research analyst and as a portfolio and mutual fund manager. During his tenure as a sell side analyst, Rob was a senior member of Piper Jaffray's Technology and Communications teams. Prior to joining Piper, Rob led Josephthal & Co.'s Washington-based Emerging Growth Research Group. In addition to his sell-side experience Rob served as Chief Investment Officer of a boutique investment management firm and Blue and White Investment Management, where he managed Small Cap Growth portfolios and The Blue and White Fund.

Analyst Certification
I, Robert Goldman, hereby certify that the view expressed in this research report accurately reflect my personal views about the subject securities and issuers. I also certify that no part of my compensation was, is, or will be, directly or indirectly, related to the recommendations or views expressed in this research report. 

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