Unprecedented Diabetes Research Collaboration to Lead to Expedited
PharmaCyte Biotech Clinical Trials
One of the untold stories behind PharmaCyte Biotech’s (OTCQB – PMCB - $0.159) success is that the formation and implementation of its International Diabetes Consortium has already resulted in unique and unprecedented collaboration on diabetes research which should lead to expedited clinical trials. The 16-member group, which boasts top tier scientists and doctors in the field of diabetes research and treatment, has members concurrently leading PharmaCyte Biotech-related diabetes research projects in more than half a dozen universities in Europe and Asia.
Typically, preclinical research and animal studies are performed and executed one at a time. The Consortium’s multiple studies are being simultaneously implemented with slightly different designs and objectives in order to accelerate the R&D process. This streamlining should substantially reduce the time to human clinical trials.
As noted in recent press releases, PharmaCyte Biotech has the exclusive worldwide rights to use Melligen cells to treat diabetes. Melligen cells are genetically engineered from human liver cells and have been shown to secrete insulin in response to the concentrations of glucose (blood sugar) in their environment. When Melligen cells were transplanted into diabetic mice whose immune systems were essentially not functioning, the blood glucose levels of the mice became normal. This observation illustrates that Melligen cells can reverse the diabetic condition.
Today, all members of the Consortium are committed to developing a treatment for insulin-dependent diabetes using PharmaCyte Biotech's Cell-in-a-Box® cellulose-based live-cell encapsulation technology combined with human non-pancreatic, insulin-producing cells (Melligen Cells). To swiftly reach this objective, Consortium members are leveraging their individual strengths and animal studies capabilities, by using their unique models to work concurrently and in tandem. As a result, the Consortium’s diabetes research studies may be some of the comprehensive concurrent efforts undertaken in years.
Once all of the mice studies are completed, PharmaCyte Biotech can leverage the Consortium’s research facilities and personnel at leading universities and companies to migrate to pig studies, since pigs are biologically and anatomically close to humans and the pig trials will thus lead to human clinical trials. Upon successful completion of these Cell-in-a-Box®/Melligen tests, the Company will move to the clinic in order to demonstrate the reversal of diabetes in humans.
The value proposition provided PharmaCyte Biotech in the Consortium’s efforts is clear and a higher valuation should be afforded the Company each time a key research stage is completed, which should occur in the coming quarters, and as outlined above.
For more information, refer to our previous sponsored PMCB Reports, Updates and Hot Topic Articles by visiting http://www.GoldmanResearch.com/
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Senior Analyst: Robert Goldman
Rob Goldman founded Goldman Small Cap Research in 2009 and has over 20 years of investment and company research experience as a senior research analyst and as a portfolio and mutual fund manager. During his tenure as a sell side analyst, Rob was a senior member of Piper Jaffray's Technology and Communications teams. Prior to joining Piper, Rob led Josephthal & Co.'s Washington-based Emerging Growth Research Group. In addition to his sell-side experience Rob served as Chief Investment Officer of a boutique investment management firm and Blue and White Investment Management, where he managed Small Cap Growth portfolios and The Blue and White Fund.
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